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PLoS ONE: Familial Linkage between Neuropsychiatric Disorders and Intellectual Interests

Students aspiring to technical majors (science/mathematics/engineering) were more likely than other students to report a sibling with an autism spectrum disorder (p = 0.037). Conversely, students interested in the humanities were more likely to report a family member with major depressive disorder (p = 8.8×10−4), bipolar disorder (p = 0.027), or substance abuse problems (p = 1.9×10−6). A combined PREdisposition for Subject MattEr (PRESUME) score based on these disorders was strongly predictive of subject matter interests (p = 9.6×10−8). Our results suggest that shared genetic (and perhaps environmental) factors may both predispose for heritable neuropsychiatric disorders and influence the development of intellectual interests.

This fascinating study looks at some of the fine points of familial inheritance, extending to what subjects interest you if you’re ancestors had depression, autism or other mental conditions–MentalHealthMomBlog

PLoS ONE: Familial Linkage between Neuropsychiatric Disorders and Intellectual Interests.

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